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Understanding the Connection between Infections, our Immune System and the Brain - Case studies: Autoimmune Brain Panel
Webinar Info
- Speaker: Craig Shimasaki, PhD, MBA – President & CEO, Moleculera Biosciences
- Aired: October 17, 2024
ABOUT THE WEBINAR
The Autoimmune Brain Panel™ (formerly known as the Cunningham Panel™) is an aid in a clinician’s diagnosis of autoimmune encephalopathy and basal ganglia encephalitis disorders. Neurologic, psychiatric, and behavioral symptoms can result from a number of different etiologies. When the underlying root is an autoimmune encephalopathy or basal ganglia encephalitis, treatments that have shown effectiveness include anti-infectives, anti-inflammatory and immune modulatory modalities.
This free educational webinar will explain the clinical significance of autoimmune antibodies against brain and neuronal targets, and the types of symptoms that have been associated with them. We will review some of the most common presenting symptoms associated with positive Autoimmune Brain Panel™ results, and share published clinical data on patients’ before and after effective treatment.
Attendees will gain a strong understanding of the biology behind infection-triggered autoimmune neuropsychiatric disorders, the most common patient symptoms, and how to utilize the Autoimmune Brain Panel™ test results in treatment decisions.
Scroll through the video to watch specific chapters. Click below.
1:42 – Disorders diagnosed by symptoms, not etiology
2:43 – Acute vs chronic inflammation
3:30 – Infections associated with various symptoms
6:30 – Long-COVID and an immune response
7:19 – How does this occur biologically?
10:15 – Autoantibodies attack basal ganglia
15:40 – Infections associated with autoimmune neuropsychiatric symptoms
16:23 – What is molecular mimicry?
19:01 – Case study: 8-year-old with multiple neuropsychiatric symptoms
20:58 – Case study: 16-year-old with OCD, tics, food restriction
23:47 – Case study: 20-year-old with OCD, other neuropsychiatric symptoms
25:57 – Case study: 15-year-old misdiagnosed with schizophrenia
27:15 – Symptoms correlating with Panel biomarkers
29:51 – Published studies on Autoimmune Brain Panel
30:13 – Precision medicine approach
36:40 – Overview of diagnosis and treatment
PRESENTER
Craig Shimasaki is President and CEO of Moleculera Biosciences, a neuroimmunology precision medicine company focused on identifying underlying roots of neurologic, psychiatric, and behavioral disorders triggered by an autoimmune response. He is a medical research scientist with over 35 years of translational development experience in biochemical interactions, molecular biology, viral pathogenesis and infection-triggered neuropsychiatric disorders.
Dr. Shimasaki has worked at all stages of research and development from bench to bedside. His research included epitope mapping of HIV proteins, genetic based risk predictors of breast cancer, influenza and RSV diagnostics and therapeutics and pathogenesis of infection triggered neuropsychiatric disorders. As a businessperson, he co-founded multiple companies and led multiple products through the FDA approval process and is a co-inventor on multiple patents.
Dr. Shimasaki started his career at Genentech. He received his BS in Biochemistry from University of California at Davis, his PhD in Molecular Biology from the University of Tulsa, and his MBA from Northwestern University, Kellogg School of Business. He is an Adjunct Professor at the University of Oklahoma where he teaches biotechnology entrepreneurship. His passion is to help translate scientific and medical discoveries into acutely needed products so that more patients can live healthier lives.
Disclosure
This webinar is intended only for Medical Professionals.
The webinar content has been made available for informational purposes only. The information provided is not intended to be medical or healthcare advice for any individual medical problem, nor a substitute for medical or professional advice and services from a qualified healthcare provider.
By attending or viewing the webinar, you acknowledge and agree that we have not represented that any content provided in this webinar has the ability to diagnose a medical condition, prescribe treatment, or perform any other tasks that constitute the practice of medicine.
Moleculera hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the webinar content, which is provided as is, and without warranties.
All rights reserved. No part of this presentation may be reproduced, distributed, or transmitted in any form or by any means, including recording, photocopying, or other electronic or other methods without the prior written consent of the publisher.